Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS.
Yu D, Cheeseman F, Vanner S
GI Diseases Research Unit, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada.
Published 7 February 2011 in Gut, 60(3): 334-40.
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Articles on Irritable Bowel Syndrome published 24 January 2011:
Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome. J Med Microbiol, 60: 236-45.
Intestinal microbiota may play a role in the pathophysiology of irritable bowel syndrome (IBS). In this case-control study, mucosa-associated small intestinal and faecal microbiota of IBS patients and healthy subjects were analysed using molecular-based methods. Duodenal mucosal brush and faecal samples were collected from 37 IBS patients and 20 healthy subjects. The bacterial 16S rRNA gene was amplified and analysed using PCR denaturing gradient gel electrophoresis (DGGE). Pooled average DGGE ... [Abstract] [Full-text]
Articles on Irritable Bowel Syndrome published 6 January 2011:
Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med, 364(1): 22-32.
[Abstract] [Full-text]
Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med, 364(1): 22-32.
[Abstract] [Full-text]
Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med, 364(1): 22-32.
[Abstract] [Full-text]
Articles on Irritable Bowel Syndrome published 21 December 2010:
Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology, 140(1): 91-100.
[Abstract] [Full-text]
Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology, 140(1): 91-100.
[Abstract] [Full-text]
Articles on Irritable Bowel Syndrome published 3 December 2010:
Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation. Gastroenterology, 139(6): 1877-1886.e2.
[Abstract] [Full-text]
Bacterial metabolic 'toxins': a new mechanism for lactose and food intolerance, and irritable bowel syndrome. Toxicology, 278(3): 268-76.
Lactose and food intolerance cause a wide range of gut and systemic symptoms, including gas, gut pain, diarrhoea or constipation, severe headaches, severe fatigue, loss of cognitive functions such as concentration, memory and reasoning, muscle and joint pain, heart palpitations, and a variety of allergies (Matthews and Campbell, 2000; Matthews et al., 2005; Waud et al., 2008). These can be explained by the production of toxic metabolites from gut bacteria, as a result of anaerobic digestion of ... [Abstract] [Full-text]
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